Hirata Y, Takahashi M, Yamada Y, Matsui R, Inoue A, Ashida R, et al. trans-Fatty acids promote p53-dependent apoptosis triggered by cisplatin-induced DNA interstrand crosslinks via the Nox-RIP1-ASK1-MAPK pathway. Sci Rep. 2021;11:10350.
Hirata Y, Inoue A, Suzuki S, Takahashi M, Matsui R, Kono N, et al. trans-Fatty acids facilitate DNA damage-induced apoptosis through the mitochondrial JNK-Sab-ROS positive feedback loop. Sci Rep. 2020;10:2743.
Hirata Y, Nada Y, Yamada Y, Toyama T, f*ckunaga K, Hwang GW, et al. Elaidic acid potentiates extracellular ATP-induced apoptosis via the P2X. Biol Pharm Bull. 2020;43:1562–9.
Hirata Y, Takahashi M, Kudoh Y, Kano K, Kawana H, Makide K, et al. -Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway. J Biol Chem. 2017;292:8174–85.
Yamada M, Suzuki M, Noguchi T, Yokosawa T, Sekiguchi Y, Mutoh N, et al. The Antibiotic Cefotaxime Works as Both an Activator of Nrf2 and an Inducer of HSP70 in Mammalian Cells. BPB Rep. 2020;3:16–21.
Suzuki M, Asai Y, Kagi T, Noguchi T, Yamada M, Hirata Y, et al. TAK1 mediates ROS generation triggered by the specific cephalosporins through noncanonical mechanisms. Int J Mol Sci. 2020;21:9497.
Kudoh Y, Noguchi T, Ishii C, Maeda K, Nishidate A, Hirata Y, et al. Antibiotic vancomycin promotes the gene expression of NOD-like receptor families in macrophages. BPB Rep. 2018;1:6–10.
Noguchi T, Suzuki M, Mutoh N, Hirata Y, Tsuchida M, Miyagawa S, et al. Nuclear-accumulated SQSTM1/p62-based ALIS act as microdomains sensing cellular stresses and triggering oxidative stress-induced parthanatos. Cell Death Dis. 2018;9:1193.
Yuan Z, Tam VH. Polymyxin B: a new strategy for multidrug-resistant Gram-negative organisms. Expert Opin Investig Drugs. 2008;17:661–8.
Zavascki AP, Goldani LZ, Li J, Nation RL. Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review. J Antimicrob Chemother. 2007;60:1206–15.
Zavascki AP, Nation RL. Nephrotoxicity of polymyxins: is there any difference between colistimethate and polymyxin B? Antimicrob Agents Ch. 2017;61:e02319–16.
Zheng G, Cao L, Che Z, Mao E, Chen E, He J. Polymyxin B-induced skin hyperpigmentation: a rare case report and literature review. BMC Pharm Toxicol. 2018;19:41.
Gupta S, Govil D, Kakar PN, Prakash O, Arora D, Das S, et al. Colistin and polymyxin B: a re-emergence. Indian J Crit Care Med. 2009;13:49–53.
Falagas ME, Kasiakou SK. Toxicity of polymyxins: a systematic review of the evidence from old and recent studies. Crit Care. 2006;10:R27.
Mulay SR, Linkermann A, Anders HJ. Necroinflammation in kidney disease. J Am Soc Nephrology: JASN. 2016;27:27–39.
Yokosawa T, Yamada M, Noguchi T, Suzuki S, Hirata Y, Matsuzawa A. Pro-caspase-3 protects cells from polymyxin B-induced cytotoxicity by preventing ROS accumulation. J Antibiot (Tokyo). 2019;72:848–52.
Anders HJ. Of Inflammasomes and alarmins: IL-1beta and IL-1alpha in kidney disease. J Am Soc Nephrology: JASN. 2016;27:2564–75.
Asavarut P, Zhao H, Gu J, Ma D. The role of HMGB1 in inflammation-mediated organ injury. Acta anaesthesiologica Taiwanica: Off J Taiwan Soc Anesthesiologists. 2013;51:28–33.
Schroder K, Tschopp J. The inflammasomes. Cell. 2010;140:821–32.
Evavold CL, Ruan J, Tan Y, Xia S, Wu H, Kagan JC. The pore-forming protein gasdermin D regulates interleukin-1 secretion from living macrophages. Immunity. 2018;48:35–44 e36.
Anders HJ, Muruve DA. The inflammasomes in kidney disease. J Am Soc Nephrology: JASN. 2011;22:1007–18.
Noguchi T, Sekiguchi Y, Kudoh Y, Naganuma R, Kagi T, Nishidate A, et al. Gefitinib initiates sterile inflammation by promoting IL-1β and HMGB1 release via two distinct mechanisms. Cell Death Dis. 2021;12:49.
Kagi T, Noguchi T, Matsuzawa A. Mechanisms of gefitinib-induced interstitial pneumonitis: why and how the TKI perturbs innate immune systems? Oncotarget. 2021;12:1321–2.
Lu B, Wang H, Andersson U, Tracey KJ. Regulation of HMGB1 release by inflammasomes. Protein cell. 2013;4:163–7.
Durkin ME, Qian X, Popescu NC, Lowy DR. Isolation of Mouse Embryo Fibroblasts. Bio-protocol. 2013;3:e908.
Noguchi T, Ishii K, f*ckutomi H, Naguro I, Matsuzawa A, Takeda K, et al. Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage. J Biol Chem. 2008;283:7657–65.
Fujishiro H, Yano Y, Takada Y, Tanihara M, Himeno S. Roles of ZIP8, ZIP14, and DMT1 in transport of cadmium and manganese in mouse kidney proximal tubule cells. Metallomics. 2012;4:700–8.
Noguchi T, Tsuchida M, Kogue Y, Spadini C, Hirata Y, Matsuzawa A. Brefeldin A-inhibited guanine nucleotide-exchange factor 1 (BIG1) governs the recruitment of tumor necrosis factor receptor-associated factor 2 (TRAF2) to Tumor necrosis factor receptor 1 (TNFR1) signaling complexes. Int J Mol Sci. 2016;17:1869.
Shimada T, Kudoh Y, Noguchi T, Kagi T, Suzuki M, Tsuchida M, et al. The E3 ubiquitin-protein ligase RNF4 promotes TNF-alpha-induced cell death triggered by RIPK1. Int J Mol Sci. 2021;22:5796.
Tsuchida M, Yokosawa T, Noguchi T, Shimada T, Yamada M, Sekiguchi Y, et al. Pro-apoptotic functions of TRAF2 in p53-mediated apoptosis induced by cisplatin. J Toxicol Sci. 2020;45:219–26.
Naito Y, Hino K, Bono H, Ui-Tei K. CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites. Bioinformatics. 2015;31:1120–3.
Sanjana NE, Shalem O, Zhang F. Improved vectors and genome-wide libraries for CRISPR screening. Nat Methods. 2014;11:783–4.
Sekiguchi Y, Yamada M, Noguchi T, Noomote C, Tsuchida M, Kudoh Y, et al. The anti-cancer drug gefitinib accelerates Fas-mediated apoptosis by enhancing caspase-8 activation in cancer cells. J Toxicol Sci. 2019;44:435–40.
Hirata Y, Katagiri K, Nagaoka K, Morish*ta T, Kudoh Y, Hatta T, et al. TRIM48 promotes ASK1 activation and cell death through ubiquitination-dependent degradation of the ASK1-negative regulator PRMT1. Cell Rep. 2017;21:2447–57.
Toyama T, Hoshi T, Noguchi T, Saito Y, Matsuzawa A, Naganuma A, et al. Methylmercury induces neuronal cell death by inducing TNF-alpha expression through the ASK1/p38 signaling pathway in microglia. Sci Rep. 2021;11:9832.
Azad MA, Finnin BA, Poudyal A, Davis K, Li J, Hill PA, et al. Polymyxin B induces apoptosis in kidney proximal tubular cells. Antimicrob Agents Chemother. 2013;57:4329–35.
Avedissian SN, Liu J, Rhodes NJ, Lee A, Pais GM, Hauser AR, et al. A review of the clinical pharmaco*kinetics of polymyxin B. Antibiotics (Basel). 2019;8:31.
Zavascki AP, Goldani LZ, Cao G, Superti SV, Lutz L, Barth AL, et al. Pharmaco*kinetics of intravenous polymyxin B in critically ill patients. Clin Infect Dis: Off Publ Infect Dis Soc Am. 2008;47:1298–304.
Chen Q, Guan X, Zuo X, Wang J, Yin W. The role of high mobility group box 1 (HMGB1) in the pathogenesis of kidney diseases. Acta Pharm Sin B. 2016;6:183–8.
Paudel YN, Shaikh MF, Chakraborti A, Kumari Y, Aledo-Serrano A, Aleksovska K, et al. HMGB1: a common biomarker and potential target for TBI, neuroinflammation, epilepsy, and cognitive dysfunction. Front Neurosci. 2018;12:628.
Allam R, Darisipudi MN, Rupanagudi KV, Lichtnekert J, Tschopp J, Anders HJ. Cutting edge: cyclic polypeptide and aminoglycoside antibiotics trigger IL-1beta secretion by activating the NLRP3 inflammasome. J Immunol. 2011;186:2714–8.
Yun B, Zhang T, Azad MAK, Wang J, Nowell CJ, Kalitsis P, et al. Polymyxin B causes DNA damage in HK-2 cells and mice. Arch Toxicol. 2018;92:2259–71.
Hermsen ED, Sullivan CJ, Rotschafer JC. Polymyxins: pharmacology, pharmaco*kinetics, pharmacodynamics, and clinical applications. Infect Dis Clin North Am. 2003;17:545–62.
Zani IA, Stephen SL, Mughal NA, Russell D, Homer-Vanniasinkam S, Wheatcroft SB, et al. Scavenger receptor structure and function in health and disease. Cells. 2015;4:178–201.
Thakur SA, Hamilton RF Jr, Holian A. Role of scavenger receptor a family in lung inflammation from exposure to environmental particles. J Immunotoxicol. 2008;5:151–7.
Kanno S, Furuyama A, Hirano S. A murine scavenger receptor MARCO recognizes polystyrene nanoparticles. Toxicol Sci. 2007;97:398–406.
